SCHOOL DIRECTORS

Laura Barisoni, M.D.
Duke University, Durham, NC, USA

Loreto Gesualdo, M.D.
University of Bari, Italy

Matthias Kretzler, M.D., PhD.
University of Michigan, Ann Arbor, MI, USA

Surya V. Seshan, M.D.
Cornell University, NY, USA

SCHOOL FRAMEWORK

The CME-accredited International Summer School of Renal Pathology & Precision Medicine (ISSRPPM) will be held at the University of Bari in June 2024 with state-of-the-art facilities. This educational endeavor is dedicated to advancing knowledge and improving management of kidney disease. The school builds on previous experience gained through the International Summer School of Renal Pathology (ISSRP) since 2011 and aims to train the next generation of renal pathologists to practice integrated nephropathology.

The school will be organized in 4 modules:

  • Precision Medicine – Basic Concepts from tissue procurement to data extraction and analysis
  • Pathology of Native Kidney Diseases with clinico-patholologic and molecular correlation
  • Digital Pathology and Image Analysis of Kidney Diseases
  • Molecular Nephropathology & Data Integration

Each module will include:

  • Formal educational lectures
    – Renal Pathology
    – Image analysis
    – Omics technologies
  • Hands-on laboratory experience in small groups
    – Case review and case study in small groups with trainer
    – Image analysis
    – Relevant Omics technologies
  • Data integration & phenotyping-endotyping – Case studies 

CURRICULUM

RENAL PATHOLOGY OF NATIVE KIDNEY DISEASES

  • Podocytopathies
  • Mitochondriopathies
  • Collagenopathies
  • Immune-complex-mediated glomerulonephritis
  • Complement-mediated glomerulonephritis
  • Crescentic glomerulonephritis
  • Vascular diseases
  • Monoclonal diseases of renal significance & organized renal deposits
  • Diabetic kidney disease
  • Chronic kidney disease
  • Tubulointerstitial diseases
  • Renal storage diseases

COMPUTATIONAL IMAGE ANALYSIS

  • Principles of digital pathology
  • Histo-tools
  • Annotation-segmentation best practices
  • Machine Learning classifiers
  • Pathomic feature extraction
  • Digital biomarkers
  • Visualization tools
  • Image analysis in clinical practice

MOLECULAR NEPHROPATHOLOGY

  • Genetics of kidney diseases
  • Technologies and analytical approaches in kidney tissue and biofluids
  • Spatial omics analysis
  • Multiscale data integration
  • Principles of data mining strategies and interfaces
  • Specific search engines
  • Data integration

EXECUTIVE COMMITTEE

Laura Barisoni
Duke University, USA
Matthias Kretzler
University of Michigan, USA
Surya V. Seshan
Cornell University, USA
Loreto Gesualdo
University di Bari, Italy

STEERING COMMITTEE

Tarek M. Ashkar
Indiana University School of Medicine, Indianapolis, IN, USA
Peter Boor
Uniklinik RWTH Aachen, Germany
Tobias B. Huber
Universitätsklinikum Hamburg-Eppendorf, Germany
Sanjay Jain
Washington University in St. Louis, St. Louis, MO, USA
Andrew R. Janowczyk
Emory University, Atlanta, GA, USA
Rafael Kramann
Uniklinik RWTH Aachen, Germany
Laura Mariani
University of Michigan Health, Ann Arbor, MI, USA
Francesco Pesce
Ospedale Isola Tiberina – Gemelli Isola, Rome, Italy
Victor Puelles Universitätsklinikum Hamburg-Eppendorf, Germany
Pierre Ronco
INSERM and University Pierre et Marie Curie – Hôpital Tenon, Paris, France
John Sedor
Cleveland Clinic’s Lerner Research Institute, Cleveland, OH, USA
John E. Tomatzsewski
Jacobs School of Medicine and Biomedical Science, Buffalo, NY, USA

FACULTY

TBD

Endorsement